Changing treatment landscape of Marginal zone lymphoma
نویسندگان
چکیده
منابع مشابه
Splenic marginal zone lymphoma.
Splenic marginal zone lymphoma (SMZL) is a specific low-grade small B-cell lymphoma that is incorporated in the World Health Organization classification. Characteristic features are splenomegaly, moderate lymphocytosis with villous morphology, intrasinusoidal pattern of involvement of various organs, especially bone marrow, and relative indolent course. Tumor progression with increase of blasti...
متن کاملRadiotherapy in marginal zone lymphoma
PURPOSE To evaluate the efficacy of radiotherapy (RT) for early-stage nodal and extranodal marginal zone lymphoma (MZL). MATERIALS AND METHODS Patients with stage I (n = 22) and stage II (n = 8) MZL, who were treated with RT were reviewed. The primary tumor localisation was in the orbita (n = 12), stomach (n = 8), head and neck other than the orbita (n = 8), breast (n = 1) and one case of mar...
متن کاملMarginal Zone B-cell lymphoma
Extra-nodal MZBCL of MALT type (7% of all NHL) is an indolent disease involving most often the stomach, where it usually follows chronic gastritis due to Helicobacter pylori (HP) infection. The disease may also localize in the lung, the thyroid, the salivary gland, the orbit. Splenic MZBCL (1% of all NHL on histologic samples) usually, though not invariably, presents splenomegaly associated cir...
متن کاملNon-hodgkin’s Malignant Marginal Zone Lymphoma: Diagnosis and Treatment
The principles of therapeutic tactics in patients with indolent non-Hodgkin’s B-cell lymphomas are presented. The results of clinical trials that studied different regimens (with usable chemotherapy, target, radiation therapy, hematopoietic stem cells transplantation) of treatment of patients with this disease are summarized. Data on morphological, immunophenotypical and molecular-biological ch...
متن کاملSurgical management of splenic marginal zone lymphoma.
OBJECTIVES Splenic marginal zone lymphoma (SMZL) is a rare indolent B-cell lymphoma with variable prognosis. As a result, there is sparse knowledge on the role of splenectomy and best management approaches. We aim to explore management strategies and outcomes amongst the cohort of SMZL patients at our centre. METHOD A retrospective review of all splenectomies performed at a tertiary referral ...
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ژورنال
عنوان ژورنال: Integrative Clinical Medicine
سال: 2019
ISSN: 2515-0219
DOI: 10.15761/icm.1000159